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Biometric Research Program (BRP)

Dr. Mariam Konate Monnard

Computational Biologist, Computational & Systems Biology Branch


Research Interests

Biomarker discovery, integrative genomics, cancer epigenetics, gene expression analysis, structural bioinformatics


Selected Recent Publications:

Monks A, Zhao Y, Hose C, Hamed H, Krushkal J, Fang J, Sonkin D, Palmisano A, Polley E, Fogli L, Konate M, Miller S, Simpson M, Voth A, Li M-C, Harris E, Wu X, Connelly J, Rapisarda A, Teicher B, Simon R, Doroshow JH. The NCI Transcriptional Pharmacodynamics Workbench: a tool to examine dynamic expression profiling of therapeutic response in the NCI-60 cell line panel. Cancer Research, 78: 6807-6817, 2018.

Antony S, Jiang G, Wu Y, Meitzler JL, Makhlouf HR, Haines DC, Butcher D, Hoon DS, Ji J, Zhang Y, Juhasz A, Lu J, Liu H, Dahan I, Konate M, Roy KK, Doroshow JH. NADPH oxidase 5 (NOX5)-induced reactive oxygen signaling modulates normoxic HIF-1α and p27Kip1 expression in malignant melanoma and other human tumors. Molecular Carcinogenesis, 56:2643-2662, 2017.

Lu J, Risbood P, Kane CT Jr, Hossain MT, Anderson L, Hill K, Monks A, Wu Y, Antony S, Juhasz A, Liu H, Jiang G, Harris E, Roy K, Meitzler JL, Konate M, Doroshow JH. Characterization of potent and selective iodonium-class inhibitors of NADPH oxidases. Biochemical Pharmacology, 143:25-38, 2017.

Konate MM, Plata G, Park J, Wang HH, Vitkup V. Molecular function limits divergent protein evolution on planetary timescales. BioRxiv, 198663, 2017.

Gallagher SS, Jing C, Peterka DS, Konate M, Wombacher R, Kaufman LJ, Yuste R, Cornish VW. A trimethoprim-based chemical tag for live cell two-photon imaging. Chembiochem, 11:782-784, 2010.



Dr. Mariam Konate

Office Address:
Room 5W116
9609 Medical Center Dr
Rockville, MD 20850

Contact Information:
Tel: (240) 276-6273
Fax: (240) 276-7888
Email:mariam.konate@nih.gov