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Biometric Research Program (BRP)

Dr. Ming-Chung Li

Mathematical Statistician, Computational & Systems Biology Branch


Research Interests

Statistical computing, classification and prediction, non-linear time series.


Selected Peer Reviewed Papers:

Monks A, Zhao Y, Hose C, Hamed H, Krushkal J, Fang J, Sonkin D, Palmisano A, Polley E, Fogli L, Konate M, Miller S, Simpson M, Voth A, Li M-C, Harris E, Wu X, Connelly J, Rapisarda A, Teicher B, Simon R, Doroshow JH.The NCI Transcriptional Pharmacodynamics Workbench: a tool to examine dynamic expression profiling of therapeutic response in the NCI-60 cell line panel. Cancer Research, 78: 6807-6817, 2018.

Palmisano A, Zhao Y., Li MC, Polley EC, Simon R. OpenGeneMed: a portable, flexible and customizable informatics hub for the coordination of next-generation sequencing studies in support of precision medicine trials, Brief Bioinformatics (2016) doi: 10.1093/bib/bbw059

Zhao Y, Polley E, Li MC, Lih CJ, Palmisano A, Sims D, Rubinstein L, Conley B, Chen A, Williams PM, Kummar S, Doroshow JH, Simon RM. GeneMed: an informatics hub for the coordination of next-generation sequencing studies that support precision oncology clinical trials, Cancer Informatics, 2015, 14(Suppl 2):45-55.

Wang SJ, Li MC. Impacts of Predictive Genomic Classifier Performance on Subpoplation-Specific Treatment Effects Assessment. Statistics in Biosciences, doi:10.1007/s12561-013-9092-y 2013

Simon R, Subramanian J, Li MC, and Menezes S. Using Cross-Validation to Evaluate Predictive Accuracy of Survival Risk Classifiers Based on High Dimensional Data. Briefings in Bioinformatics, 2011.

Korn E, Li MC, McShane LM, and Simon R. An Investigation of Two Multivariate Permutation Methods for Controlling the False Discovery Proportion, Statistics in Medicine 2007; 26, pp4428-4440.

Li MC, Chan KS. Multivariate reduced-rank nonlinear time series modeling, Statistica Sinica 2007:17, 139:159.

Simon R, Lam A, Li MC, Ngan M, Menenzes S, Zhao Y. Analysis of gene expression data using BRB-array tools. Cancer Informatics, vol. 3, pp. 11.17, 2007.

Zhao Y, Li MC, Simon R. An adaptive method for cDNA microarray normalization. BMC Bioinformatics 6:28, 2005.



Dr. Ming-Chung Li

Office Address:
Room 5W620
9609 Medical Center Dr
Rockville, MD 20850

Contact Information:
Tel: (240) 276-6147
Fax: (240) 276-7888
Email:limingc@mail.nih.gov