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Biometric Research Program (BRP)

Dr. Julia Krushkal Adkins

Computational Biologist, Computational & Systems Biology Branch


Research Interests

Bioinformatic analysis of genome sequence, expression, and epigenetic data, analysis of molecular determinants of drug response of cancer cell lines, statistical genetics, genetic epidemiology


CV (Updated April, 2019)


Selected Recent Publications:

Krushkal J, Qu Y, Lovley DR, Adkins RM. Phylogenetic classification of diverse LysR-type transcriptional regulators of a model prokaryote Geobacter sulfurreducens. Journal of Molecular Evolution, 74:187-205, 2012.

Adkins RM, Tylavsky FA, Krushkal J. Newborn umbilical cord blood DNA methylation and gene expression levels exhibit limited association with birth weight. Chemistry and Biodiversity, 9:888-899, 2012.

Krushkal J, Murphy LE, Palmer FB, Graff JC, Hovinga CA, Mozhui K, Thomas F, Park V, Sutter TR, Tylavsky FA, Adkins RM. Epigenetic analysis of neurocognitive development at 1 year of age in a community-based pregnancy cohort, Behavior Genetics, 44:113-125, 2014.

Krushkal J, Zhao Y, Hose C, Monks A, Doroshow JK, Simon R. Concerted changes in transcriptional regulation of genes involved in DNA methylation, demethylation, and folate-mediated one-carbon metabolism pathways in the NCI-60 cancer cell line panel in response to cancer drug treatment, Clinical Epigenetics, 8:73, 2016.

Greenwood CMT, Xu C, Alam S, Krushkal J, Adkins RM, Naumova AK. Genetic and epigenetic variation at the H19 imprinted region and its effect on birth weight, Book chapter in: Epigenetics in human reproduction and development. A.K. Naumova and T.Taketo, Eds. World Scientific Publishing. pp. 185-207, 2017.

Krushkal J, Zhao Y, Hose C, Monks A, Doroshow JH, Simon R. Longitudinal transcriptional response of glycosylation related genes, regulators, and targets in cancer cell lines treated with eleven antitumor agents. Cancer Informatics, 16:1-14, 2017.

Teicher BA, Silvers T, Selby M, Delosh R, Laudeman J, Ogle C, Reinhart R, Parchment R, Krushkal J, Sonkin D, Rubinstein L, Morris J, Evans D. Small cell lung carcinoma cell line screen of etoposide/carboplatin plus a third agent. Cancer Medicine, 6:1952-1964, 2017.

Monks A, Zhao Y, Hose C, Hamed H, Krushkal J, Fang J, Sonkin D, Palmisano A, Polley E, Fogli L, Konate M, Miller S, Simpson M, Voth A, Li M-C, Harris E, Wu X, Connelly J, Rapisarda A, Teicher B, Simon R, Doroshow JH.The NCI Transcriptional Pharmacodynamics Workbench: a tool to examine dynamic expression profiling of therapeutic response in the NCI-60 cell line panel. Cancer Research, 78: 6807-6817, 2018.

Vural S, Simon R, Krushkal J. Correlation of gene expression and associated mutation profiles of APOBEC3A, APOBEC3B, REV1, UNG, and FHIT with chemosensitivity of cancer cell lines to drug treatment. Human Genomics, 12:20, 2018.



Dr. Julia Krushkal Adkins

Office Address:
Room 5W116
9609 Medical Center Dr
Rockville, MD 20850

Contact Information:
Tel: (240) 276-5988
Fax: (240) 276-7888
Email:julia.krushkal@nih.gov