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Breast Cancer Classification and Prognosis Based on Gene Expression Profiles from a Population-Based - Full-Text Plus! - all 7 versions
C Sotiriou, SY Neo, LM McShane, EL Korn, PM Long, … - Proceedings of the National Academy of Sciences of the …, 2003 - National Acad Sciences
... Hierarchical agglomerative clustering using the statis- tical package BRB - ARRAYTOOLS
software (available at http: linus.nci.nih.gov BRB-ArrayTools.html) was ...
Cited by 339 - Related Articles - Web Search

Methods for assessing reproducibility of clustering patterns observed in analyses of microarray data - Full-Text Plus! - all 7 versions
LM McShane, MD Radmacher, B Freidlin, R Yu, MC Li, … - Bioinformatics, 2002 - Oxford Univ Press
... Availability: Software to implement these methods is contained in BRB ArrayTools
microarray analysis package available from http://linus.nci.nih.gov./BRB ...
Cited by 96 - Related Articles - Web Search

Molecular Classification of Tamoxifen-Resistant Breast Carcinomas by Gene Expression Profiling - Full-Text Plus! - all 5 versions
MPHM Jansen, JA Foekens, IL van Staveren, MM … - Journal of Clinical Oncology, 2005 - jco.ascopubs.org
... packages BRB Array Tools, developed by the Biometric Research Branch of the US National
Cancer Institute (http://linus.nci.nih.gov/BRB-ArrayTools.html) and ...
Cited by 81 - Related Articles - Web Search

De Novo Kidney Transplantation Without Use of Calcineurin Inhibitors Preserves Renal Structure and … - Full-Text Plus! - all 9 versions
SM Flechner, SM Kurian, K Solez, DJ Cook, JT Burke … - American Journal of Transplantation, 2004 - pt.wkhealth.com
... BRB ArrayTools ( http://linus.nci.nih.gov/BRB-ArrayTools.html ) was used to perform
class comparisons between the two drug treatment or Banff score-defined ...
Cited by 101 - Related Articles - Web Search

Laser Capture Microdissection and Microarray Expression Analysis of Lung Adenocarcinoma Reveals … - Full-Text Plus! - all 3 versions
K Miura, ED Bowman, R Simon, AC Peng, AI Robles, … - Cancer Research, 2002 - AACR
... The analyses were performed using BRB-ArrayTools. 5. Hierarchical Clustering. ... 5 Simon,
R., and Peng, A. BRB-ArrayTools Users Guide. National Cancer Institute. ...
Cited by 79 - Related Articles - Web Search

Kidney Transplant Rejection and Tissue Injury by Gene Profiling of Biopsies and Peripheral Blood … - Full-Text Plus! - all 6 versions
SM Flechner, SM Kurian, SR Head, SM Sharp, TC … - American Journal of Transplantation, 2004 - pt.wkhealth.com
... We used six class predictors implemented in BRB ArrayTools for determining to ... six
class prediction algorithms currently available in BRB Array Tools for both ...
Cited by 49 - Related Articles - Web Search

Expression Profiling of Serous Low Malignant Potential, Low-Grade, and High-Grade Tumors of the … - Full-Text Plus! - all 3 versions
T Bonome, JY Lee, DC Park, M Radonovich, C Pise- … - Cancer Research, 2005 - AACR
... BRB ArrayTools is a multifunctional Excel add-in that contains utilities for processing
and analyzing microarray data using the R version 2.0.1 environment (R ...
Cited by 30 - Related Articles - Web Search

Gene expression patterns for doxorubicin (Adriamycin) and cyclophosphamide (Cytoxan)(AC) response … - Full-Text Plus! - all 4 versions
S Cleator, A Tsimelzon, A Ashworth, M Dowsett, T … - Breast Cancer Research and Treatment, 2006 - Springer
... and analyzed by dChip (http://www.dchip.org) [7] and classifiers were constructed
with BRB Array Tools (http://linus.nci.nih.gov/BRB-ArrayTools.html) [8]. ...
Cited by 15 - Related Articles - Web Search

Gene expression in peripheral blood mononuclear cells from patients with chronic fatigue syndrome - all 10 versions
N Kaushik, D Fear, SCM Richards, CR McDermott, EF … - British Medical Journal, 2005 - jcp.bmj.com
... by Dr R Simon and A Peng (http://linus.nci.nih.gov/BRB-ArrayTools.html). ... CFS; n =
25) and normal persons (n = 25) identified by analysis in BRB Array Tools. ...
Cited by 32 - Related Articles - Web Search

Analysis of gene expression in cancer cell lines identifies candidate markers for pancreatic … - Full-Text Plus! - all 3 versions
E Missiaglia, E Blaveri, B Terris, YH Wang, E … - International Journal of Cancer, 2004 - doi.wiley.com
... Statistical class comparison The data were also analyzed using BRB-ArrayTools (version
3.0; http://linus.nci.nih.gov/BRB-ArrayTools.html) developed by Dr. ...
Cited by 32 - Related Articles - Web Search

The p53 Tumor Suppressor Network Is a Key Responder to Microenvironmental Components of Chronic … - all 4 versions
F Staib, AI Robles, L Varticovski, XW Wang, BR … - Cancer Research, 1714 - AACR
... the following software for data analysis: BRB Array Tools developed by Dr. Richard
Simon and Amy Peng Lam (http://linus.nci.nih.gov/BRB-ArrayTools.html), High ...
Cited by 16 - Related Articles - Web Search - Full-Text Plus!

[PDF] Gene microarray analysis of peripheral blood cells in pulmonary arterial hypertension. - Full-Text Plus! - all 7 versions
TM Bull, CD Coldren, M Moore, SM Sotto-Santiago, … - American Journal of Respiratory and Critical Care Medicine, 2004 - 171.66.122.149
... The array data were analyzed with BRB ArrayTools v3.0.2E developed by Dr. Richard
Simon and Amy Tan. ... and class prediction functions of BRB ArrayTools. ...
Cited by 28 - Related Articles - View as HTML - Web Search

Cancer-associated molecular signature in the tissue samples of patients with cirrhosis - Full-Text Plus! - all 4 versions
JW Kim, Q Ye, M Forgues, Y Chen, A Budhu, J Sime, … - Hepatology, 2004 - doi.wiley.com
... All analyses were performed using the BRB ArrayTools (version 3.0 ... that more complex
SVMs perform less well for this application (R. Simon, BRB Array Tools manual ...
Cited by 26 - Related Articles - Web Search

Evaluation of a linear amplification method for small samples used on high-density oligonucleotide … - Full-Text Plus! - all 3 versions
CI Dumur, CT Garrett, KJ Archer, S Nasim, DS … - Analytical Biochemistry, 2004 - Elsevier
... we applied to identify differentially expressed genes was the paired t test as
implemented in the Class Comparison tool available in BRB-ArrayTools v3.0.2 [15 ...
Cited by 19 - Related Articles - Web Search

Condensin binding at distinct and specific chromosomal sites in the Saccharomyces cerevisiae genome - Full-Text Plus! - all 4 versions
BD Wang, D Eyre, M Basrai, M Lichten, A Strunnikov - Mol. Cell. Biol, 2005 - pubmedcentral.nih.gov
... BRB-Array Tools (http://linus.nci.nih.gov/BRB-ArrayTools.html) software was used
to validate the reproducibility of hybridization replicas (within each array ...
Cited by 16 - Related Articles - Web Search

Expression Profiles of Osteosarcoma That Can Predict Response to Chemotherapy - all 3 versions
TK Man, M Chintagumpala, J Visvanathan, J Shen, L … - Cancer Research, 985 - AACR
... experiments were subjected to data analysis using BRB Array Tools 3.1.0 developed
by R. Simon and A. Pang Lam (http://linus.nci.nih.gov/BRB-ArrayTools.html). ...
Cited by 15 - Related Articles - Web Search - Full-Text Plus!

Transcript profiling of human platelets using microarray and serial analysis of gene expression - Full-Text Plus! - all 5 versions
DV Gnatenko, JJ Dunn, SR McCorkle, D Weissmann, PL … - Blood, 2003 - bloodjournal.hematologylibrary.org
... Microarray data were visualized and analyzed using BRB-ArrayTools software (Version
2.1), kindly developed and provided by Dr Richard Simon and Amy Peng (linus ...
Cited by 236 - Related Articles - Web Search

Identification by Real-time PCR of 13 mature microRNAs differentially expressed in colorectal cancer … - Full-Text Plus! - all 9 versions
E Bandrés, E Cubedo, X Agirre, R Malumbres, R … - Molecular Cancer, 2006 - pubmedcentral.nih.gov
... samples, two multivariate permutation test provided in BRB-ArrayTools were performed ...
attempted to use the class prediction tool (BRB-Array tools) that creates a ...
Cited by 29 - Related Articles - Web Search

Cryptococcus neoformans Gene Expression during Murine Macrophage Infection - Full-Text Plus! - all 6 versions
W Fan, PR Kraus, MJ Boily, J Heitman - Eukaryotic Cell, 2005 - ec.highwire.org
... Pro v 4.0 and BRB array tools (developed by Richard Simon and Amy Peng Lam at the
National Cancer Institute; http://linus.nci.nih.gov/BRB-ArrayTools.html). ...
Cited by 16 - Related Articles - Web Search

Analysis of Orthologous Gene Expression between Human Pulmonary Adenocarcinoma and a Carcinogen- … - Full-Text Plus! - all 6 versions
RS Stearman, L Dwyer-Nield, L Zerbe, SA Blaine, Z … - American Journal of Pathology, 2005 - ASIP
... BRB-ArrayTools has several classification/prediction modes we used for ... Further,
BRB-Array Tools includes five different algorithms for class prediction that ...
Cited by 14 - Related Articles - Web Search

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Gene Expression Profiling of Microsatellite Unstable and Microsatellite Stable Endometrial Cancers … - all 3 versions
JI Risinger, GL Maxwell, GVR Chandramouli, O … - Cancer Research, 850 - AACR
... BRB Array tools ver. 3.0c, Richard Simon, Amy Peng, Biometric research branch, National
Cancer Institute, NIH; http://linus.nci.nih.gov/BRB-ArrayTools.html). ...
Cited by 11 - Related Articles - Web Search - Full-Text Plus!

Signatures of differentially regulated interferon gene expression and vasculotrophism in the … - Full-Text Plus! - all 5 versions
FK Tan, X Zhou, MD Mayes, P Gourh, X Guo, C Marcum … - Rheumatology, 2006 - Br Soc Rheumatology
... The program BRB ArrayTools v. 3.2, designed by Richard Simon and Amy Peng Lam ... Next,
using BRB Array Tools, we examined known biological pathways in order to ...
Cited by 16 - Related Articles - Web Search - BL Direct

Gene profiling of scleroderma skin reveals robust signatures of disease that are imperfectly … - all 3 versions
H Gardner, JR Shearstone, R Bandaru, T Crowell, M … - Arthritis Rheum, 2006 - doi.wiley.com
... Data were analyzed using the BRB ArrayTools system. When appropriate, findings were
followed up with immunohistochemical analysis or TaqMan studies. Results. ...
Cited by 11 - Related Articles - Web Search - Full-Text Plus! - BL Direct

Lung Adenocarcinoma Global Profiling Identifies Type II Transforming Growth Factor-{beta} Receptor … - Full-Text Plus! - all 5 versions
AC Borczuk, HK Kim, HA Yegen, RA Friedman, CA … - American Journal of Respiratory and Critical Care Medicine, 2005 - 171.66.122.149
... supervised analysis using an F test within BRB array tools (developed by Richard
Simon and Amy Peng Lam; http://linus.nci.nih.gov/BRB-ArrayTools.html) to ...
Cited by 10 - Related Articles - Web Search

Molecular mechanisms of West Nile virus pathogenesis in brain cell - Full-Text Plus! - all 4 versions
WL Koh, ML Ng - Emerg Infect Dis, 2005 - cdc.gov
... Analyses of the scanned microarray images were performed with BRB ArrayTools version
3.1 (developed by R. Simon and AP Lam, National Cancer Institute, Bethesda ...
Cited by 8 - Related Articles - Cached - Web Search

[PDF] Gene Expression Profiles in Paraffin-Embedded Core Biopsy Tissue Predict Response to Chemotherapy in … - Full-Text Plus! - all 9 versions
L Gianni, M Zambetti, K Clark, J Baker, M Cronin, … - Journal of Clinical Oncology, 2005 - jco.ascopubs.org
... Statistical analysis was per- formed by using the BRB-Arraytools software package
(http:// linus.nci.nih.gov/BRB-ArrayTools.html). RESULTS ...
Cited by 97 - Related Articles - View as HTML - Web Search

Differential gene expression profiles in stage I primary biliary cirrhosis - Full-Text Plus! - all 3 versions
M Honda, H Kawai, Y Shirota, T Yamashita, S Kaneko - Am J Gastroenterol, 2005 - Blackwell Synergy
... Hierarchical clustering of gene expression of the patients was performed by
BRB-ArrayTools ( http:/ / linus.nci.nih.gov/ BRB-ArrayTools.html ). ...
Cited by 8 - Related Articles - Web Search

Alterations in the expression of DEAD-box and other RNA binding proteins during HIV-1 replication - all 10 versions
V Krishnan, SL Zeichner - feedback, 2005 - retrovirology.com
... Using BRB -ArrayTools http://linus.nci.nih.gov/BRB-ArrayTools, the data were subjected
to statistical analyses using univariate parametric and multivariate ...
Cited by 11 - Related Articles - Cached - Web Search

Gene expression profile of cervical tissue compared to exfoliated cells: Impact on biomarker … - all 4 versions
M Steinau, DR Lee, MS Rajeevan, SD Vernon, MT … - feedback, 2005 - biomedcentral.com
... (1) BRB Array Tools 3.2 http://linus.nci.nih.gov/BRB-ArrayTools: Log 2 transformed
sARM values were normalized over the median of each array and subjected to a ...
Cited by 9 - Related Articles - Cached - Web Search

Differential gene alteration among hepatoma cell lines demonstrated by cDNA microarray-based … - Full-Text Plus! - all 3 versions
K Kawaguchi, M Honda, T Yamashita, Y Shirota, S … - Biochemical and Biophysical Research Communications, 2005 - Elsevier
... BRB-Array Tools Ver. 3.1.0 (http://linus.nci.nih.gov/BRB-ArrayTools.html) were used
to compare gene amplification in AFP-producing and AFP-negative hepatoma ...
Cited by 7 - Related Articles - Web Search

Distinct Transcriptional Changes in Donor Kidneys upon Brain Death Induction in Rats: Insights in … - Full-Text Plus! - all 4 versions
TA Schuurs, F Gerbens, JAB van der Hoeven, PJ … - American Journal of Transplantation, 2004 - pt.wkhealth.com
... To account for dye bias, resulting data were normalized by intensity-dependent
regression (Lowess) of the log-transformed ratios by BRB ArrayTools version 3.0 ...
Cited by 13 - Related Articles - Web Search

[CITATION] Independent Validation of Prognostic Relevance of a Previously Reported Gene-Expression Signature in … - Full-Text Plus!
G Marcucci, MD Radmacher, AS Ruppert, K Mrozek, JE … - Blood, 2005 - 2005, The American Society of Hematology
Cited by 9 - Related Articles - Web Search

Unique microRNA molecular profiles in lung cancer diagnosis and prognosis - Full-Text Plus! - all 13 versions
N Yanaihara, N Caplen, E Bowman, M Seike, K … - Cancer Cell, 2006 - Elsevier
... A univariate Cox proportional hazard regression model with global permutation test
in BRB-ArrayTools indicated that eight miRNAs (hsa-mir-155, hsa-mir-17-3p ...
Cited by 114 - Related Articles - Web Search

The role of microRNA genes in papillary thyroid carcinoma - all 5 versions
H He, K Jazdzewski, W Li, S Liyanarachchi, R Nagy, … - Proc Natl Acad Sci US A, 2005 - pubmedcentral.nih.gov
... Raw data from miRNA chips were assembled by using BRB ArrayTools (Richard Simon
and Amy Peng Lam, National Cancer Institute, Bethesda). ...
Cited by 86 - Related Articles - Web Search

Serum Proteome to Predict Virologic Response in Patients With Hepatitis C Treated by Pegylated … - all 3 versions
V Paradis, T Asselah, D Dargere, MP Ripault, M … - Gastroenterology, 2006 - Elsevier
... For class prediction, we used the class prediction tool from BRB-ArrayTools, version
3.1.0 (available at http://linus.nci.nih.gov/BRB-ArrayTools.html). ...
Cited by 22 - Related Articles - Web Search - Full-Text Plus!

A Paradigm for Class Prediction Using Gene Expression Pro les - Full-Text Plus! - all 7 versions
MD RADMACHER, LM MCSHANE, R SIMON - JOURNAL OF COMPUTATIONAL BIOLOGY, 2002 - liebertonline.com
... value is closer to C 2 . Compound covariate prediction is implemented in BRB ArrayTools,
a visualization and statistical analysis software package for ...
Cited by 106 - Related Articles - Web Search

Downregulation in components of the mitochondrial electron transport chain in the postmortem frontal … - Full-Text Plus! - all 5 versions
X Sun, JF Wang, M Tseng, LT Young - J Psychiatry Neurosci, 2006 - pubmedcentral.nih.gov
... Analyses were performed using BRB ArrayTools developed by Dr. Richard Simon and
Amy Peng Lam (http://linus.nci.nih.gov/BRB-ArrayTools.html, Biometric Research ...
Cited by 9 - Related Articles - Web Search - BL Direct

Elevated Levels of the 64-kDa Cleavage Stimulatory Factor (CstF-64) in Lipopolysaccharide-stimulated … - Full-Text Plus! - all 2 versions
SA Shell, C Hesse, SM Morris Jr, C Milcarek - Journal of Biological Chemistry, 2005 - ASBMB
... was performed as described under "Materials and Methods" using BRB Array Tools
developed by the National Cancer Institute (linus.nci.nih.gov/BRB-ArrayTools.html ...
Cited by 12 - Related Articles - Web Search

A two-gene expression ratio predicts clinical outcome in breast cancer patients treated with … - Full-Text Plus! - all 17 versions
XJ Ma, Z Wang, PD Ryan, SJ Isakoff, A Barmettler, … - Cancer Cell, 2004 - Elsevier
... Identification and permutation testing for significance of differential gene expression
were performed using BRB ArrayTools, developed by Richard Simon and Amy ...
Cited by 180 - Related Articles - Web Search

Human immunodeficiency virus type 1 Vpr-dependent cell cycle arrest through a mitogen-activated … - Full-Text Plus! - all 4 versions
N Yoshizuka, Y Yoshizuka-Chadani, V Krishnan, SL … - J. Virol, 2005 - pubmedcentral.nih.gov
... was performed with univariate parametric and multivariate permutation tests based
on the one-sample random-variance statistic in BRB-ArrayTools (http://linus ...
Cited by 9 - Related Articles - Web Search

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Hepatocellular carcinoma in HCV-infected patients awaiting liver transplantation: Genes involved in … - Full-Text Plus! - all 3 versions
VR Mas, DG Maluf, R Stravitz, CI Dumur, B Clark, C … - Liver Transplantation, 2004 - doi.wiley.com
... we created 3 expression-value data sets for every pool of samples, which were then
converted by taking loga- rithms of base 2 using BRB ArrayTools version 3.0.2 ...
Cited by 9 - Related Articles - Web Search

Laparoscopic donor nephrectomy gene expression profiling reveals upregulation of stress and ischemia … - Full-Text Plus! - all 4 versions
SM Kurian, SM Flechner, J Kaouk, C Modlin, D … - Transplantation, 2005 - transplantjournal.com
... comparison between the control and LDN kidneys using BRB Array Tools on all ... Clustering
was done in BRB ArrayTools using centered correlation and average linkage ...
Cited by 6 - Related Articles - Web Search

Molecular profiling of malignant peritoneal mesothelioma identifies the ubiquitin–proteasome … - Full-Text Plus! - all 5 versions
AC Borczuk, GCA Cappellini, HK Kim, M Hesdorffer, … - Oncogene, 2007 - nature.com
... agglomerative hierarchical clustering within BRB array tools (developed by Richard
Simon and Amy Peng Lam; http://linus.nci.nih.gov/BRB-ArrayTools.html) using ...
Cited by 6 -