Dr. Edward L. Korn

Office Address:
Room 8128
6130 Executive Plaza
Rockville, MD 20852

Contact Information:
Tel: (301) 402-0635
Fax: (301) 402-0560
Email: Korne@ctep.nci.nih.gov

Research Interests
Categorical data analysis, Clinical trials methodology, Multiple comparisons, Survey methods research, Survival analysis.

Selected Recent Publications

As of March 10, 2006

Korn EL and Graubard BI. Analysis of Health Surveys. New York: John Wiley and Sons, 1999. 

Korn EL, Teeter DM and Baumrind S. Using explicit clinician preferences in nonrandomized study designs. Journal of Statistical Planning and Inference 96: 67-82, 2001 

Korn EL, Arbuck SG, Pluda JM, Simon R, Kaplan RS, and Christian MC. Clinical trial designs for cytostatic agents: Are new approaches needed? Journal of Clinical Oncology 19: 265-272, 2001 

Korn EL, Arbuck SG, Pluda JM, Simon R, Kaplan RS, and Christian MC. Reply to Ratain and Stadler (letter). Journal of Clinical Oncology 19: 3154-3155, 2001. 

Freidlin B and Korn EL. A testing procedure for survival data with few responders. Statistics in Medicine 21: 65-78, 2002. 

Freidlin B, Dancey J, Korn EL, Zee B, and Eisenhauer E. Multinomial phase II trial designs (letter). Journal of Clinical Oncology 20: 599, 2002. 

Albert PS, McShane LM, and Korn EL. Design of a binary biomarker study from the results of a pilot study.  Biometrics 58: 576-585, 2002.

Graubard BI and Korn EL. Inference for superpopulation parameters using sample surveys. Statistical Science 17: 73-96, 2002. 

Korn EL, McShane LM, Troendle JF, Rosenwald A, and Simon R. Identifying pre-post chemotherapy differences in gene expression in breast tumors: A statistical method appropriate for this aim. British Journal of Cancer 86: 1093-1096, 2002. 

Freidlin B and Korn EL. A comment on futility monitoring. Controlled Clinical Trials 23: 355-366, 2002. 

Korn EL and Graubard BI. Estimating variance components using survey data. Journal of the Royal Statistical Society B  65:175-190, 2003 

Simon RM, Korn EL, McShane LM, Radmacher MD, Wright GW and Zhao Y.  Design and Analysis of DNA Microarray Investigations.  New York: Springer, 2003

Sotiriou C, Neo S-Y, McShane LM, Korn EL, Long PM, Jazaeri A, Martiat P, Fox SB, Harris AL and Liu ET.  Breast cancer classification and prognosis based on gene expression profiles from a population-based study.  PNAS 100: 10393-10398, 2003.

Korn EL, Troendle JF, McShane LM and Simon R.  Controlling the number of false discoveries: application to high-dimensional genomic data.  Journal of Statistical Planning and Inference 124: 379-398, 2004.

Freidlin B and Korn EL.  Erythropoietin to treat anaemia in patients with head and neck cancer (letter).  Lancet 353: 81, 2004. 

Troendle JF, Korn EL, and McShane LM.  An example of slow convergence of the bootstrap in high dimensions. American Statistician 58: 25-29, 2004.

Korn, EL, Freidlin, B, and George SL.  Data monitoring and large apparent treatment effects (letter).  Controlled Clinical Trials 25: 67-69, 2004.

Freidlin B and Korn EL. A testing procedure for survival data with few responders (letter). Statistics in Medicine 23: 1818-1823, 2004.

Korn EL, Habermann JK, Upender MB, Ried T and McShane LM. Objective method of comparing DNA microarray image analysis systems.  BioTechniques 36: 960-967, 2004.

Korn EL. Nontoxicity endpoints in phase I trial designs for targeted, non-cytotoxic agents.  Journal of the National Cancer Institute 96: 977-978, 2004.

Dodd LE, Korn EL, McShane LM, Chandramouli GVR and Chang EY.  Correcting log ratios for signal saturation in cDNA microarrays. Bioinformatics 20: 96-967, 2004.

Upender MB, Habermann JK, McShane LM, Korn EL, Barrett JC, Difilippantonio MJ, and Ried T. Chromosome transfer induced aneuploidy results in complex dysregulation of the cellular transcriptome in immortalized cancer cells.Cancer Research 64: 6941-6949, 2004.

George S, Freidlin B and Korn EL. Strength of accumulating evidence and data monitoring committee decision making. Statistics in Medicine 23: 2659-2672, 2004.

Korn EL, Albert PS and McShane LM. Assessing surrogates as trial endpoints using mixed models (with discussion). Statistics in Medicine 24:163-190, 2005.

Freidlin B and Korn EL. Testing treatment effects in the presence of competing risks.Statistics in Medicine 24: 1703-1712, 2005.

Hunsberger S, Rubinstein LV, Dancey J, and Korn EL. Dose escalation trial designs based on a molecularly targeted endpoint. Statistics in Medicine 24: 2171-2181, 2005.

Rubinstein LV, Korn EL, Freidlin B, Hunsberger SA, Ivy P, and Smith MA. Randomized phase 2 design issues and a proposal for phase II screening trials, Journal of Clinical Oncology 23: 7199-7206, 2005.

Korn EL, Hunsberger S, Freidlin B, Smith MA, and Abrams JS. Preliminary data release for randomized clinical trials of noninferiority: a new proposal.Journal of Clinical Oncology 23: 5831-5836, 2005.

Korn EL and Freidlin B. (in press) The likelihood as statistical evidence in multiple comparisons in clinical trials: no free lunch.Biometrical Journal


Please send comments and suggestions to brb@linus.nci.nih.gov

Last updated: March 10, 2006